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Psoriasis
Psoriasis - a disease of the skin of the person wearing a chronic character. Psoriasis is a dermatosis and is not an infection. To date, there is the theory that psoriasis has an autoimmune nature. As a rule, external appearance of psoriasis is expressed in red dry spots on the skin. However, in some cases, no visible lesions are not observed. These spots are called - psoriatic plaques.
These
spots are inflamed skin with excessive proliferation of lymphocytes,
macrophages, and the excess occurrence of small vessels in the adjacent
layer of the skin. These
factors lead to a thickening of the skin to the inflamed sites, some of
its "elevated" in comparison with healthy skin, as well as the
appearance characteristic of the disease pale gray spots resembling
drops of melted wax or paraffin.
At the beginning of plaque formation in the field of friction or pressure, that is, elbow, knees and buttocks. But they can appear on other parts of the body, such as the scalp, palms, feet, genitals. In contrast to eczema rash in most cases is located on the outer surfaces of the joints, but not in the folds.
Psoriasis is chronic and usually flows in waves. Periods of remission are replaced by exacerbations of the disease under the influence of different factors and recurrence. These negative factors can be alcohol, stress, disease and other diseases so on. The
severity of the disease may be different for different people and even a
single patient at different periods, ranging from a few plaques coating
and finishing of the skin of man, the whole body. If
untreated, the disease is progressing to the downside, there are more
frequent exacerbations, the area of damage increases. Sometimes it's quiet, smooth course of the disease without remissions and exacerbations.
Quite often affected are the nail plates on the arms and legs. In such cases, the disease known as psoriatic onihodistrofiya. This phenomenon can be observed in conjunction with skin lesions, and isolation. It may also occur psoriatic arthritis - the defeat of joint disease. Approximately 10-15% suffer from exactly this variety of psoriasis.
As to why the emergence and development of the disease, they so far have not been established. Scientists believe that the major role played by genetic predisposition.
Do
factors that may give an initial impetus to the development of the
disease is likely to include skin trauma, such as prolonged friction or
pressure (perhaps because of this primary plaques appear on the elbow
and knee bends), the constant, excessive use of detergents, skin
exposure alcohol
agents, perfumes, household chemicals, as well as other diseases skin
diseases, allergies and related to her scratching certain areas of the
skin.
Adversely
affect the course of disease or a strong constant stress, alcohol
abuse, smoking, treatment of certain drugs, including some
antidepressants, medicines that contain lithium, gold and so on.
With regard to treatment of this disease, there is a huge amount of drugs and treatments. However,
taking into account the chronic nature of psoriasis and a tendency to
constant development, the treatment is difficult and long. Recover fully from the disease is not currently possible, but it is possible to achieve long-term remission, sometimes for life.
Nevertheless, the risk of resumption of psoriasis remains.
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