Current problems in therapy and prevention of psoriasis
Introduction
Treatment of psoriasis remains one of the biggest problems of therapeutic practice. In most cases, it can be safely allowed, since the methods and means of treatment of psoriasis there is quite a lot. However, the main caveat is that these treatments can provide only a temporary effect, although it is possible clinical cure and improving the lives of patients. But at the same time, almost always at the first visit to the doctor the patient hears that the disease is not treated, and it should take.
Treatment depends on the symptoms showed up, pathology, general health and condition of the nervous system. Equally important is the marital status, social status. Some patients are happy when there is a very slight improvement, but at the same time, some patients require getting rid of all the manifestations of this moment absolutely.
Psoriasis is one of the most common skin sores, they get sick about 1-3 percent of the population of the globe. And if you take the percentage of those who have a disease of the skin, then suffering from psoriasis will be around 5 percent. In the last decade has seen a increase in cases of psoriasis, the age at which it appears increasingly early, and even worse shape.
Treatment of psoriasis
Scientists around the world for many decades working on treatments for psoriasis, but to date a drug that would be completely cured of the disease. You can only block it. The patient should be kept in mind that immediate therapy is not always good, it's not a panacea for subsequent relapses. The presence of plaques on the skin of static suggests that treatment should only be carried out locally. Treatment of active forms can cause severe exacerbation and progression of the disease, psoriasis can raspolztis throughout the body.
The funds are used to treat psoriasis currently do not have a strong toxic effect on the body, contain in their composition vitamins are external agents.
Treatment with ultraviolet light
PUVA therapy is one of the most effective treatments for psoriasis as well as the disappearance of symptoms is fully 90 percent of cases. UV treatment has been practiced since 1978.
The beneficial effects of ultraviolet rays in patients with psoriasis was noted long ago. If you take photosensitizing drugs in combination with exposure to UVA rays (the rays with a wavelength), the effect is much stronger. This therapy has become real after the devices were created that emit UVA rays. The role of photosensitizers are drugs psoralens. This type of treatment is known to patients suffering from psoriasis, PUVA therapy like.
Apparatus for the treatment, looks like a simple cabin. Inside it is placed a special lamp that gives such rays UVA. The length of these rays range from 320 to 400 nm, the maximum efficiency with the length of the rays have a 350-365 nm. These devices for PUVA therapy can be made so that the patient will be positioned upright or lying down. There is also a model, where the irradiated separately the different parts of the body. This is true, for example, psoriasis of the scalp. PUVA therapy is used for severe disease.
Extensive experience in this area makes it possible to say with certainty that the use of ultraviolet light for treating psoriasis gives an excellent effect, as well as smoother skin pigmentation. An important advantage of this method is that the therapy can be repeated, it reduces the severity of the disease, as well as the period between relapses is increasing.
PUVA therapy can be used for the treatment and at an advanced stage, but it requires a preliminary cleansing the body of toxins, drug treatment of itching, sedatives, and salicylic acid. To the effect of therapy was evident need to do at least 20-30 procedures.
Selective phototherapy
This method is based on the ultraviolet rays of medium length, ie 280-320 nm. In this case, treatment is carried out without the use of photosensitizers. Installations for the treatment so you can operate and at home.
SFT is conducted on patients with no such as in the previous case, severe disease in children and, if PUVA therapy for some reason contraindicated. Of course, the result, which can be obtained in the treatment of UVA rays, not comparable to SFT. However, here more range of applications - SFT can be applied at the stage of progression when symptoms are limited and so on.
It should be noted that even people with summer and spring form of the disease with proper treatment is not the deterioration. PUVA is usually used in isolation, without other drugs, the SFT is combined with other drugs.
Retinoids We are talking about and tigazon neotigazon. This is a substance derived from vitamin A in the treatment of psoriasis have good efficiency. These drugs work by preventing keratinization of the skin. Also, these drugs stabilize the rate of cell division during mitosis.
Tigazon used for the treatment, as in isolation or in conjunction with PUVA therapy. It should be noted, and to this opinion joined by many scientists, the treatment will not only tigazon mainly compared with other drugs.
Only when it comes to pustular psoriasis, the symptoms in the treatment of tigazon quickly, the temperature returned to normal, the pustules disappear.
When combined treatment and PUVA therapy tigazon effect is much better than applying these methods separately. This practice is against severe diseases such as palmoplantar psoriasis. In combination with PUVA therapy tigazon effect is enhanced and the number of procedures can be reduced, which means that the dose of ultraviolet radiation received by patients will be much less. The drug is less toxic neotigazo and more efficient.
This group of medications is contraindicated, in part because some of its properties, it is not used for the treatment of younger women.
Vitamin D
In the past few years, this type of therapy given enough attention. Typically, vitamin D is synthesized due to the transformation of sterols under the influence of temperature and ultraviolet radiation. Of great importance in the production of vitamin is human skin. Property of vitamin D has a beneficial effect on the development of psoriasis was found completely by accident in the treatment of patients with osteoporosis. There is a substance that promotes the natural production of vitamin, but it would take months. Calcipotriol is a synthetic substitute and included as a component in various ointments, one of which is psorkutan.
Introduction
Treatment of psoriasis remains one of the biggest problems of therapeutic practice. In most cases, it can be safely allowed, since the methods and means of treatment of psoriasis there is quite a lot. However, the main caveat is that these treatments can provide only a temporary effect, although it is possible clinical cure and improving the lives of patients. But at the same time, almost always at the first visit to the doctor the patient hears that the disease is not treated, and it should take.
Treatment depends on the symptoms showed up, pathology, general health and condition of the nervous system. Equally important is the marital status, social status. Some patients are happy when there is a very slight improvement, but at the same time, some patients require getting rid of all the manifestations of this moment absolutely.
Psoriasis is one of the most common skin sores, they get sick about 1-3 percent of the population of the globe. And if you take the percentage of those who have a disease of the skin, then suffering from psoriasis will be around 5 percent. In the last decade has seen a increase in cases of psoriasis, the age at which it appears increasingly early, and even worse shape.
Treatment of psoriasis
Scientists around the world for many decades working on treatments for psoriasis, but to date a drug that would be completely cured of the disease. You can only block it. The patient should be kept in mind that immediate therapy is not always good, it's not a panacea for subsequent relapses. The presence of plaques on the skin of static suggests that treatment should only be carried out locally. Treatment of active forms can cause severe exacerbation and progression of the disease, psoriasis can raspolztis throughout the body.
The funds are used to treat psoriasis currently do not have a strong toxic effect on the body, contain in their composition vitamins are external agents.
Treatment with ultraviolet light
PUVA therapy is one of the most effective treatments for psoriasis as well as the disappearance of symptoms is fully 90 percent of cases. UV treatment has been practiced since 1978.
The beneficial effects of ultraviolet rays in patients with psoriasis was noted long ago. If you take photosensitizing drugs in combination with exposure to UVA rays (the rays with a wavelength), the effect is much stronger. This therapy has become real after the devices were created that emit UVA rays. The role of photosensitizers are drugs psoralens. This type of treatment is known to patients suffering from psoriasis, PUVA therapy like.
Apparatus for the treatment, looks like a simple cabin. Inside it is placed a special lamp that gives such rays UVA. The length of these rays range from 320 to 400 nm, the maximum efficiency with the length of the rays have a 350-365 nm. These devices for PUVA therapy can be made so that the patient will be positioned upright or lying down. There is also a model, where the irradiated separately the different parts of the body. This is true, for example, psoriasis of the scalp. PUVA therapy is used for severe disease.
Extensive experience in this area makes it possible to say with certainty that the use of ultraviolet light for treating psoriasis gives an excellent effect, as well as smoother skin pigmentation. An important advantage of this method is that the therapy can be repeated, it reduces the severity of the disease, as well as the period between relapses is increasing.
PUVA therapy can be used for the treatment and at an advanced stage, but it requires a preliminary cleansing the body of toxins, drug treatment of itching, sedatives, and salicylic acid. To the effect of therapy was evident need to do at least 20-30 procedures.
Selective phototherapy
This method is based on the ultraviolet rays of medium length, ie 280-320 nm. In this case, treatment is carried out without the use of photosensitizers. Installations for the treatment so you can operate and at home.
SFT is conducted on patients with no such as in the previous case, severe disease in children and, if PUVA therapy for some reason contraindicated. Of course, the result, which can be obtained in the treatment of UVA rays, not comparable to SFT. However, here more range of applications - SFT can be applied at the stage of progression when symptoms are limited and so on.
It should be noted that even people with summer and spring form of the disease with proper treatment is not the deterioration. PUVA is usually used in isolation, without other drugs, the SFT is combined with other drugs.
Retinoids We are talking about and tigazon neotigazon. This is a substance derived from vitamin A in the treatment of psoriasis have good efficiency. These drugs work by preventing keratinization of the skin. Also, these drugs stabilize the rate of cell division during mitosis.
Tigazon used for the treatment, as in isolation or in conjunction with PUVA therapy. It should be noted, and to this opinion joined by many scientists, the treatment will not only tigazon mainly compared with other drugs.
Only when it comes to pustular psoriasis, the symptoms in the treatment of tigazon quickly, the temperature returned to normal, the pustules disappear.
When combined treatment and PUVA therapy tigazon effect is much better than applying these methods separately. This practice is against severe diseases such as palmoplantar psoriasis. In combination with PUVA therapy tigazon effect is enhanced and the number of procedures can be reduced, which means that the dose of ultraviolet radiation received by patients will be much less. The drug is less toxic neotigazo and more efficient.
This group of medications is contraindicated, in part because some of its properties, it is not used for the treatment of younger women.
Vitamin D
In the past few years, this type of therapy given enough attention. Typically, vitamin D is synthesized due to the transformation of sterols under the influence of temperature and ultraviolet radiation. Of great importance in the production of vitamin is human skin. Property of vitamin D has a beneficial effect on the development of psoriasis was found completely by accident in the treatment of patients with osteoporosis. There is a substance that promotes the natural production of vitamin, but it would take months. Calcipotriol is a synthetic substitute and included as a component in various ointments, one of which is psorkutan.
Immunosuppressive therapy The vast majority of existing drugs as systemic and local effects have a suppressive effect. There are special drugs that are intended to limit the activity of certain cells, corresponding to characteristic progression of the disease. These drugs include methotrexate and cyclosporine A.
Metrotreksat inhibits the action of folic acid, that is, the cells simply stop dividing. Used to treat skin diseases have become the drug in the 70s of last century. This drug has an extensive list of side effects which include nausea, mucous membranes, liver, and kidneys. For this reason, it is widely used in treatment is not. In addition, after treatment of exacerbation starts very quickly. However, categorically refuse to use it, too, is not worth it, especially in cases where other methods failed.
Cyclosporin A is composed of eleven amino acids and is a natural medication produced by fungi. This drug is used in the '70s when transplanting organs so that they do not he rent and to treat certain skin diseases. Its effectiveness is due to the action on the body. Apply this medication is in severe forms of the disease when other treatments do not help. Also, do not use it for patients with kidney disease, alcohol dependence, it can not be combined with treatment with ultraviolet light and certain drugs. You can not treat them and those who suffer from infectious diseases, oncology patients.
Statistics show that the drug does not impair the patient's condition, with the abolition of all side effects disappear. The downside is that a significant portion of patients one week after treatment began to return of symptoms.
The drug is expensive, relapse comes quickly, a lot of side effects and contraindications are doing this drug demand only in extreme, severe forms of the disease.
Detoxification treatment This method of treatment used by patients with severe forms. The most commonly used gemodez, which gives a good cleansing of toxins result. After the application process of the disease ceases to be sharp, but because he is good, so to speak, predlechebnoy stage, the appointment of PUVA therapy.
This medication can be combined with corticosteroids. In general, use of corticosteroids is not recommended.
Hemosorbtion contributes to reduction processes, the normalization of the functioning of systems. However, this drug gives only a short temporary effect. Plazmafarez the treatment of psoriasis does not result.
External treatment In the treatment of psoriasis use local products is very important. In simple cases, it is worth it to begin treatment. Very often the effect, which occurs as a result of the use of topical medications, no worse (and sometimes better) produced by systemic treatment. At the stage of progress prescribe salicylic ointment. The other two stages of the patients used stronger external funds on the basis of tar, and other hormones.
Tar in the treatment of psoriasis is applied against a long time. In Europe, it is tar from coal, we have wood. The first is more effective, but it is more toxic. Widely used and gidrantrony. To date, overseas drugs are used for synthetic substances, such as dinatrol. In nature, there hrizarobin substance, its artificial analogue is dinatrol. Dinatrol reduces the oxidation that occurs in psoriatic cells. This medication is a very "active", which explains the side effects that arise in its application. These include itching, redness, and it stains the clothes patient. Doctors dealing with the problem of psoriasis is still not very well aware of this drug.
Ointment on the basis of vitamin D.
A drug that contains a synthetic vitamin D - calcipotriol. It shall apply from the end of the 80s. In our country it is known as psorkutan. In the treatment of them 95 percent of patients achieved a clinical cure. You can use it in the stationary phase of the disease.
Kortikostennye medicines Many effective drugs have unpleasant exterior of the property - they are deer clothing. But some do not have these disadvantages. Corticosteroid creams are one of these drugs. Particularly good results can be achieved by applying an ointment, which is composed of coal tar or salicylic acid. If you suffer from psoriasis of the scalp, it is advisable to buy drugs in the form of lotions, aerosols.
There are also medical shampoos on the basis of tar, zinc.
Dietary restrictions No need to sit on a certain diet. Just give up drinking alcohol, fatty foods and not overeating.
Climatotherapy Staying at the resorts and sanatoriums have not only a curative effect, but also useful as a prophylactic. Now popular resorts on the Dead Sea in Israel, on the Black Sea. The main factor here - ultraviolet irradiation. Also, water from the Dead Sea has a special combination of minerals and salts that provide a healing effect.
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